Smooth Muscle Tumor Of Uncertain Malignant Potential Pathology Outlines

Smooth muscle tumor of uncertain malignant potential, abbreviated STUMP, is an uncommon. features acute inflammatory cells and a peripheral reparative process, whereas ghost outlines of nuclei are usually inconspicuous or absent. PMID 1710946.

A wide variety of markers is available, such as p63, Calponin, and smooth muscle myosin heavy chain (SMM-HC. concluded that the lesions are of uncertain malignant potential, emphasizing the.

6 days ago. Non tumor: normal Sternberg pattern approach endometrial biopsy. sarcoma NOS smooth muscle tumor of uncertain malignant potential.

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Feb 26, 2019. Best classified as a tumor of uncertain malignant potential as recurrences. both melanoma and smooth muscle markers with variable staining.

Nov 3, 2013. Smooth muscle tumours: Leiomyoma and leiomyosarcoma. These are rare tumours of uncertain malignant potential, showing an epithelioid.

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Feb 28, 2019. Prostate – Stromal tumor of uncertain malignant potential (STUMP). often positive (CD34 positivity helps rule out smooth muscle proliferations).

Aug 23, 2017. and all specimen slides were examined by the same experienced pathologist. smooth muscle tumor of uncertain malignant potential (STUMP), round shaped lesion <8 cm in diameter a with regular outline and absence.

Smooth muscle tumors are here considered an essentially dichotomous group composed of benign leiomyomas and malignant leiomyosarcomas. the designation ‘smooth muscle tumor of uncertain biologic.

Metastatic potential in parachordoma has been poorly reported in previous reports. Carstens reported a case of parachordoma in the gluteus muscle with widespread. to consider that some.

Establishing the correct diagnosis requires an index of suspicion, and appreciation of foci of more typical smooth muscle differentiation. Four additional tumors were judged of uncertain malignant.

In the past 5 years, there has been a paradigm shift in our understanding of gastrointestinal stromal tumors (GISTs). Once thought to be smooth muscle tumors. time offers real hope to patients with.

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Feb 25, 2019. 1% – 2% of uterine malignancies, but most common uterine sarcoma. Smooth muscle tumors of uncertain malignant potential (STUMP): tumor.

The following antibodies were used: vimentin (Ventana), CD34 (Ventana), muscle specific actin (MSA, Ventana), smooth. fibrous tumor of labium majus without palpable border in girls. Obstet Gynecol.

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Some patients with bland smooth muscle tumors in the uterus have synchronous or asynchronous. Nineteen such cases were retrieved from the files of the Department of Pathology at The University of.

Mar 26, 2019. Smooth muscle tumor with atypia plus either mitotic activity, tumor cell. Diagnose as tumor of uncertain malignant potential (UMP) if mitotic.

It is further optimal if the pathologist selects a tissue block for testing which will. tumor-specific breast-cell marker: BRST-2 (GCDFP-15).is it primary or metastatic ?. that it marks both benign and malignant breast epithelium [LMC-01-5927]. Paget's can be pos. smooth muscle actin (SMA): stains myofibroblasts and ME.

Glomus tumors are rare mesenchymal neoplasms with a phenotype akin to the modified smooth muscle. to associated malignant histologic characteristics. Tumors were classified based on WHO criteria as.

Although malignant neoplasms of soft tissue are relatively uncommon, Within each subset of tumors (lipomatous, smooth muscle, nerve sheath, etc.). location and extent of tumor and assay for the presence of potential metastatic lesions.. The lesional cells seem to be fibroblastic in origin but lineage remains uncertain.

The most common scrotal pathology is primary testicular tumor. to differentiate malignant from benign processes and guides the surgeon to identify the correct margins. Misdiagnosis or overtreatment.

Welcome to the updated version of Pathology for Urologists! This program was designed to help. Papillary Urothelial Neoplasm of Low Malignant Potential.

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benign smooth muscle tumors that exhibit atypical histologic features and unusual. also with smooth muscle tumors of uncertain malignant potential ( STUMP). Smooth MuscleTumors of the Uterus. (Outline). • Typical leiomyosarcoma.

The new and widely used designation “smooth muscle tumor of uncertain malignant potential” (STUMP) does not indicate a category of tumors between leiomyoma and leiomyosarcoma but is rather a.

and 6 smooth muscle tumors of undetermined malignant potential (STUMP)—using PHH3-labeled sections and hematoxylin and eosin (H&E)-stained slides. In the STUMP group, the MI on H&E ranged from 0 to 9.

sis, structure and evolutionary potential. Tumors Originating from Smooth Muscle Tissue. toma, malignant tumor of the peripheral nerve sheaths, displays well-defined outlines and the occasional intra-. uncertain pathogenesis that takes on an adipose diffe-. within the nontumoral pathologies: retroperitoneal fi-.

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Our study examined nonviable (‘necrotic’) regions of benign and malignant uterine smooth muscle tumors, including those in which the viable–nonviable interface had a variety of histologic features:.

The immunohistochemistry demonstrated almost all PEComas with strong positive human melanoma black and smooth muscle actin staining. Yu D, Tang S. Hepatic perivascular epithelioid cell tumor: a.

Modern Soft Tissue Pathology – edited by Markku Miettinen April 2017. Benign smooth muscle tumors, leiomyomas, and their malignant counterparts. of “ smooth muscle tumor of uncertain malignant potential” is prudent, to denote a borderline. The tumors can have complex and convoluted outlines or be oval masses.

small cell melanoma and rhabdoid melanoma all have the potential to mimic metastatic and primary neoplasms of different lineage derivations. Abnormal immunohistochemical expression of CD 34,

smooth muscle tumors, GI-schwannoma and undifferen-. pathology and differential diagnosis of GIST. Definition and. GISTs of uncertain malignant potential.

Oct 15, 2014. The term smooth uterine muscle of uncertain malignant potential (STUMPs). by surgical procedure diagnosed as STUMP on final pathology.

In addition, external factors such as prior therapeutics and sample preparation can interfere, leaving such cases defined as smooth muscle tumors of uncertain malignant potential (STUMP) with.

6 days ago. Uterus – Smooth muscle tumor of unknown malignant potential. website. https:// plus uncertain mitotic index because possible mitotic figures may be degenerating.

When compared with normal breast ducts and lobules on the same slide, myoepithelial cells associated with benign sclerosing lesions showed reduced expression of cytokeratin 5/6 in 31.8% of cases,

Thus, the current WHO classification includes adipocytic tumors, fibroblastic/myofibroblastic tumors, fibrohistiocytic tumors, tumors of smooth muscle. pathology included the concept of.